In precise genome editing, site-specific DNA double-strand breaks (DSBs) induced by the CRISPR/Cas9 system are repaired via homology-directed repair (HDR) using exogenous donor DNA templates.However, the low efficiency of HDR-mediated genome editing is a barrier to widespread use.In this study, we created a donor DNA/guide RNA (gRNA) hybrid duplex
Bacterial cellulose (BC) stands out as a prominent biopolymer of global importance, distinguished by its unique advantages over plant-derived cellulose.Strains such as Acetobacter xylinum, renowned for their proficient BC production, draw considerable attention Musical Instrument Amplifier Accessories in both commercial and biomedical areas.This re
Abstract There is a long history of considering the constituent components of malaria risk and the malaria transmission cycle via the use of mathematical models, yet strategic planning in endemic countries tends not to take full advantage of available disease intelligence to tailor interventions.National malaria programmes Blankets typically make o